Monday, May 6, 2019

Part IV: Current and future anti-aging treatments

As mentioned earlier, many antioxidants are essential nutrients. Natural antioxidants, such as vitamins C and E, work synergistically. It may be more effective to get antioxidants from a diet rich in fruits and vegetables. Nutritionists recommend eating 6 or more antioxidant-rich fruits and vegetables a day. Everyone agrees that anti-aging supplements may be helpful in anti-aging, but there is no consensus on what the most effective supplemental dose should be.

Anti-aging medicine acknowledges that stress causes aging, but has not yet been treated individually for this. There are countless sources of internal and external stress, and personal stress levels vary widely. A neglected cause of internal pressure is inadequate hydration. Water is critical to the proper operation of many internal functions. Too little or too much water can cause age stress. When a person is older [over 80 years old], the thirst feels lower and dehydration is easy to enter. Other sources of stress that are overlooked are the antioxidant itself. Supplemental antioxidants at high doses [or higher than some but not specified amounts] are known causes of stress.

To help, antioxidant supplements must prevent other types of stress more than the pressure they produce. Knowing the correct supplemental dose to do this is an important part of anti-aging treatment. A healthy young man in his twenties will have less internal pressure than a 60-year-old if he gets proper nutrition. For younger individuals, lower amounts of antioxidants may be safer than high amounts. An elderly person with many internal homeostasis mechanisms is less able to cope with internal stress and may benefit more from higher amounts of antioxidants. In theory, antioxidant-based anti-aging treatments will slow the rate of cellular damage. The cells will slowly become "ill". Over time, as fewer diseased cells are replaced at a slower rate, the number of cells retaining longer telomeres will be higher. Then you can reasonably expect this to lead to an increase in life expectancy. The current recommended but inaccurate way to reduce the incidence of cell damage is to increase the daily intake of antioxidant-rich fruits and vegetables, slightly increase the intake of antioxidants, and ingest various vitamins and a small amount of anti-virus. Daily supplements. One study showed that taking multivitamin supplements can extend telomere length.

The ideal anti-aging treatment should be fine-tuned for everyone. The key here is to measure and minimize the cumulative impact of different types of stress on an individual basis. For various types of pressure, practical biomarkers that are easy to measure are not yet available or are not used. When used, it is easy to customize the amount of individual antioxidants so that everyone has the "best" level throughout their lifetime. The "best" level will maintain a safe reserve of protective antioxidants in the body.

Next, I will briefly discuss the most popular nutrients associated with anti-aging. The most common antioxidants, vitamins and nutrients are usually associated with health and anti-aging, including: beta-carotene [vitamin A], vitamin C, vitamin E, various flavonoids, Omega-3 and omega-6 fatty acids, coenzyme Q10 , lycopene, selenium.

Dozens of supplements are known to be effective in treating specific symptoms in the elderly. Some of the more well-known supplements include: DMAE, acetyl L-carnitine, L-carnosine, lipoic acid, DHEA, L-arginine and melatonin

Good foods contain some of the antioxidants mentioned earlier. Some other popular foods related to anti-aging include: green tea, turmeric and red wine.

All of the above have unique biological characteristics, and it seems to me that if you take a small amount or a moderate amount, it is "good" for you. Some [such as vitamin C] may also be "good" for you. Various studies of each of these may conflict. You need to study each substance yourself, but researchers have found that the length of several nutrients is related to the average telomere length. These include: green tea, Omega-3, vitamins A, C, D and E.

Vitamin E is associated with telomere prolongation of anti-aging properties.

Green tea contains many antioxidants, including vitamins C, E and flavonoids. The pellets form a large class of antioxidants [including catechins and quercetin] with many anti-cancer, anti-high cholesterol, antibacterial, [helping to prevent dental caries] and anti-inflammatory properties. The leaves of the tea tree are rich in polyphenols. Drinking 3 or more cups of green tea per day is associated with longer than average telomere length.

Omega-3 is an essential long-chain polyunsaturated fatty acid with anti-inflammatory properties that help prevent heart disease, stroke, memory loss, depression, arthritis, cataracts, and cancer. Omega-3s slow down the shortening of telomeres; that is, they prevent aging at the cellular level.

Vitamin C is a rich internal water-soluble antioxidant that protects cellular components from the formation of free radicals caused by pollution and cigarette smoke. Many studies have shown that vitamin C intake is high, and the incidence of oral cancer, laryngeal cancer and esophageal cancer is low. Vitamin C shows promise in treating premature aging and possibly aging.

Since I can add a limit on the number of links in this article, I can't provide more reference links that support the previous paragraph. If you are interested, please email me at the email address shown at the end of this article and I will forward it to you.

The sooner you start some kind of anti-aging treatment, the better, but it will never be too late. All real treatments can help you maintain a longer average than the average telomere chain length.

The goal of programmed aging theory is to address the underlying causes of aging. This goal includes attempts to slow or reverse the telomere shortening process. Two such treatments are: TA 65 and human genetic engineering.

TA 65 is a telomerase activation product produced and sold by Sierra Sciences. The key component of TA 65 is xanthine, a plant extract known to have telomerase activation properties. This product may work, but I don't recommend it for several reasons. TA 65 is too expensive for ordinary people. Many expensive health spas have included the TA 65 in their plans. These are economically beyond the reach of ordinary people. Many people question the marketing strategy of Serra Science and have legal proceedings against TA 65.

One of my major problems with the TA 65 is scientific honesty. The company's genetically engineered mice can shut down and turn on telomerase at a very young age. TA 65 is able to switch telomerase in these mice and let them live a normal life. Http://www.nature.com/news/2010/101128/full/news.2010.635.html

It is dishonest to use it to show the effectiveness of TA65 treatment. This is not how telomerase usually works, and does not really extend lifespan beyond the absence of genetic modification. In normal mice, the effect of TA65 is temporary and little or no life extension is seen. Http://www.thedailybeast.com/articles/2011/04/11/anti-aging-pill-new-study-on-ta-65-sparks-controversy.html

Human genetic engineering is the real answer to fighting and defeating aging. It can directly address the root cause of aging. Advances in the field [such as CRISPR] allow for the insertion or deletion of DNA base pairs at specific locations in our DNA. This means that the human genome can now be precisely edited as needed. The use of telomerase gene therapy moderately increased the lifespan of mice. In humans, genetic modification therapy is often used in a variety of medical problems. On September 15, 2015, Elizabeth Parrish was the first to receive anti-aging gene therapy. As our understanding of the details of the human genome grows, anti-aging treatments will grow rapidly.

The current general social and political attitude seems to be conducive to the further development of anti-aging research. There are no internationally recognized political programs that can stop aging or prolong life, but since 2012, some supportive immortal parties have sprung up. Their goal is to support anti-aging and life-sustaining research and to help everyone gain progress in these areas. Among the many organizations that support anti-aging research, the SENS [Engineering Neglected Aging Strategy] organization has proposed an anti-aging research program. They hope to develop anti-aging therapies to repair most forms of cellular damage. SENS is a charity organization. Any anti-aging progress generated by the funds provided by it will become ready-made public knowledge. In addition to normal scientific research, there is the $1,000 Palo Alto Longevity Prize, which can be offered to anyone who can provide effective anti-aging treatment.

As of 2015, all known anti-aging therapies are only partially effective. Depending on when a comprehensive anti-aging program begins, one can extend the life of a person by 10 to 25 years. Researchers at the Harvard School of Public Health estimate that an anti-aging lifestyle can add 24.6 years of life to a person's life cycle. Anti-aging knowledge increases at a rate of about 10 times per 10 years. This may mean that for many of us, there is enough time to get the expected benefits of anti-aging research. In the near future, aging, like many other diseases, will be cured. When we wait for those anti-aging technology singularities to appear, the name of the game is to ensure that we stay healthy enough to repeat their benefits.



Orignal From: Part IV: Current and future anti-aging treatments

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